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Nano ChIP-Seq and RNA-Seq
We offer RNA-Seq services for Formalin-Fixed Paraffin-Embedded (FFPE) samples. Our library
preparation service accommodates low sample input and places no limits on sample quality (DV200).
Table 1: Comparison of sample requirements between Auristone and other vendors
Compared to Vendor A’s RNA-Seq library preparation on FFPE samples, Auristone delivers a
consistent yield exceeding tenfold, while maintaining a higher pass rate*.
*Pass rate refers to libraries that pass Quality Check (QC) metrics and requirements for sequencing
Table 2: Comparison of average yield and pass rate for library preparation between Auristone and Vendor A
We provide RNA-Seq data processing and analysis, including differential gene expression, gene set enrichment analysis and specific signature visualizations, among other analyses.
We are dedicated to supporting your research endeavours and accelerating your scientific journey. Our aim is to help you achieve your goals efficiently. With a focus on excellence, we offer fast turnaround times, ensuring you receive publication-ready data promptly. Should you have any additional requirements or questions, please feel free to contact us at enquiry@auristone.com.
Auristone employs a proprietary Nano-scaled Chromatin Immunoprecipitation Sequencing (Nano ChIP-Seq) workflow to explore post-translational histone modifications in samples. ChIP-Seq is a powerful technique that integrates ChIP assays with Next-Generation Sequencing (NGS) to examine interactions between DNA and proteins. The nano-scaled nature of our ChIP-Seq protocol stems from the requirement for ultra-low sample input. This ultra-sensitive technology enables a wider-range of applications for discovery, validation, and screening of genome-wide histone modifications in a reliable and efficient manner. With these capabilities, Signomax™ effectively addresses unmet needs in epigenomic biomarker discovery.
Fig 1. A snapshot of genome tracks showing regions with histone modification (peaks) using Signomax™’s Nano ChIP-Seq technology, compared with standard protocols without Signomax™
Fig 2. Bar chart showing annotation of peaks detected by Nano ChIP-Seq
Fig 3. Performance output of Signomax™’s Nano ChIP assay versus other commercially available ChIP kits
For more information on Signomax™, please contact enquiry@auristone.com
Interested in working with us? Drop us a note below and we’ll get back to you as soon as we can.
enquiry@auristone.com
LaunchPad @ one-north
73 Ayer Rajah Crescent, #02-19 Singapore 139952
